[polar]

http://news.ucdavis.edu/search/news_deta...o?id=10982

Quote:

Exposure of pregnant mice to the pesticide DDT is linked to an increased risk of obesity, diabetes, high cholesterol and related conditions in female offspring later in life, according to a study led by the University of California, Davis.

The study, published online July 30 in the journal PLOS ONE, is the first to show that developmental exposure to DDT increases the risk of females later developing metabolic syndrome -- a cluster of conditions that include increased body fat, blood glucose and cholesterol.

DDT was banned in the United States in the 1970s but continues to be used for malaria control in countries including India and South Africa.

Scientists gave mice doses of DDT comparable to exposures of people living in malaria-infested regions where it is regularly sprayed, as well as of pregnant mothers of U.S. adults who are now in their 50s.

“The women and men this study is most applicable to in the United States are currently at the age when they’re more likely to develop metabolic syndrome, because these are diseases of middle- to late adulthood,” said lead author Michele La Merrill, assistant professor of environmental toxicology at UC Davis.

The scientists found that exposure to DDT before birth slowed the metabolism of female mice and lowered their tolerance of cold temperature. This increased their likelihood of developing metabolic syndrome and its host of related conditions.

“As mammals, we have to regulate our body temperature in order to live,” La Merrill said. “We found that DDT reduced female mice’s ability to generate heat. If you’re not generating as much heat as the next guy, instead of burning calories, you’re storing them.”

The study found stark gender differences in the mice’s response to DDT. Females were at higher risk of obesity, Type 2 diabetes and cholesterol, but in males, DDT exposure did not affect obesity or cholesterol levels and caused only a minor increase in glucose levels.

A high fat diet also caused female mice to have more problems with glucose, insulin and cholesterol but was not a risk factor for males. The sex differences require further research, the authors said.

[Dr. Howard]

interesting on the gender differences. I wonder if its estrogen byproduct related like estrogen compounds from plastic inducing premature puberty in girls.

I also love DDT studies and hitting environmentalists with them. Its that choice, would you rather have some fatties and birds with brittle egg shells or thousands of human deaths due to malaria, yellow fever, river blindness and other sorts of mosquito borne diseases? Even in the US...west nile and chicamungna or pesticides? hippies....

[polar]

^^ I can't find it now, but I recall ruining across a source arguing that DDT was a major reason in the rise of breast cancer, better detection aside. PubMed might have something on the matter.

Reaping the benefits of technology comes with accepting the (often unforeseen) consequences.

[TheWastelander]

Female obesity in mice.

[Ziltoid]

Quote:

A high fat diet also caused female mice to have more problems with glucose, insulin and cholesterol but was not a risk factor for males. The sex differences require further research, the authors said.

Right... So based on this mouse study, lets infer that pesticides are to blame for women being so ungodly fat, and high-carb diets are the healthiest thing ever.

[HawkWrites]

(08-13-2014 10:01 AM)Ziltoid Wrote:  

Quote:

A high fat diet also caused female mice to have more problems with glucose, insulin and cholesterol but was not a risk factor for males. The sex differences require further research, the authors said.

Right... So based on this mouse study, lets infer that pesticides are to blame for women being so ungodly fat, and high-carb diets are the healthiest thing ever.

Of course! The pesticides go straight into the leafy greens and colorful fruits so they're trying to stay away from them by not eating any goddamn vegetables at all. The perfect replacement is more fatty foods; unless they're green too!

[Texas_Tryhard]

Generally if you see an article in PLOS ONE that means it was too shit to make it into any good journals.

[Quintus Curtius]

Titles of future "academic studies" that will prove obesity is the product of some uncontrollable external factor, thus absolving people of their responsibility to control their urges:

Female Obesity Due To Earth's Gravitational Field
Female Obesity Linked To Male Facial Hair
Female Obesity Coincides With Giant Sunspots
Female Obesity Correlated With High Male Testosterone
Female Obesity Due to Exercise
Female Obesity Due To Thinking or Talking About Obesity


.

[Veloce]

(08-13-2014 04:47 PM)Quintus Curtius Wrote:  

Titles of future "academic studies" that will prove obesity is the product of some uncontrollable external factor, thus absolving people of their responsibility to control their urges:

Female Obesity Due To Earth's Gravitational Field
Female Obesity Linked To Male Facial Hair
Female Obesity Coincides With Giant Sunspots
Female Obesity Correlated With High Male Testosterone
Female Obesity Due to Exercise
Female Obesity Due To Thinking or Talking About Obesity


.

Exactly what I was thinking.

"Big boned"
"Thyroid disease"
"Gluten/Dairy/Meat/Nightshade/Allium/Nut Allergy"
"Genes"
"Mercury is in retrograde"