Posts: 1,355
Threads: 0
Joined: Jan 2016
Reputation:
9
Science of Staying Young Forever - Google Is Now Involved
05-25-2016, 11:56 PM
Honestly science is overrated; the only major discoveries in recent times have been the Human Genome Project and Hubble Space Telescope.
We can't even cure the common cold yet expect science to make us live forever; if anything "science" has just become an atheist/progressive equivalent to religion, but with Jesus' second coming and the rapture merely replaced with Ray Kurzweil inventing a cyberspace version of "heaven" where we can live forever as computer AIs.
Posts: 4,649
Threads: 0
Joined: Feb 2013
Reputation:
107
Science of Staying Young Forever - Google Is Now Involved
05-26-2016, 12:06 AM
You haven't seen anything yet silver member, buckle up.
SENS Foundation - help stop age-related diseases
Quote: (05-19-2016 12:01 PM)Giovonny Wrote:
If I talk to 100 19 year old girls, at least one of them is getting fucked!
Quote:WestIndianArchie Wrote:
Am I reacting to her? No pussy, all problems
Or
Is she reacting to me? All pussy, no problems
Posts: 164
Threads: 0
Joined: Mar 2016
Science of Staying Young Forever - Google Is Now Involved
05-26-2016, 01:31 AM
What people dont seem to get is that the human body is DESIGNED to age and die. There are animals that dont age, we are not one of them.
It seems that the model of birth-aging-death is the one nature has selected as the best one for us.
I suppose it may be related to evolution, if you believe in such a crazy theory.
Posts: 4,649
Threads: 0
Joined: Feb 2013
Reputation:
107
Science of Staying Young Forever - Google Is Now Involved
05-26-2016, 01:40 AM
^^ Okay now the stuff up there is just crazy a head transplant? I don't know if I would want to be connected to some other guy's dead body. I am a fan of just replacing dead and bad cells with new ones created from your existing genome. So it is still completely yourself. Like repainting a house.
I am very leery of all the mind upload to a computer, robot bodies, other human bodies. I would need to see the technology in action over time, even seeing that could irk me for whatever reason deep down.
I am also very distrusting of cryo freezing after you die, who knows how you could be "brought back" in what form and by what type of being that may exist in some insane future. All these I have listed are really about fear of loss of control and spirit.
If someone injects some super stem cells made from my own DNA into me that clear out my bad cells and replenish old with young ones to rebuild my tissue and blood I am cool with that. In fact athletes do this now to heal injuries all the time now on a smaller scale.
^ Yeah and we are designed to get polio, and the plague, and eaten by wolves and bears. What the fuck happened to all that? Some people are designed to get muscle atrophy disease, some are designed to be retarded.
SENS Foundation - help stop age-related diseases
Quote: (05-19-2016 12:01 PM)Giovonny Wrote:
If I talk to 100 19 year old girls, at least one of them is getting fucked!
Quote:WestIndianArchie Wrote:
Am I reacting to her? No pussy, all problems
Or
Is she reacting to me? All pussy, no problems
Posts: 4,649
Threads: 0
Joined: Feb 2013
Reputation:
107
Science of Staying Young Forever - Google Is Now Involved
05-26-2016, 01:59 AM
I just have to reiterate it is mindblowing to me the mental gymnastics people pull off to not accept infectious disease as something people should naturally let happen to them.
These same people would be pro-for finding a cure to cancer.
Then they don't realize cancer is a disease of aging first and foremost. There are some from environmental factors, vast majority are from aging and make for terrible deaths.
So infectious disease BAD! Ok to cure! Aging disease... I don't like them! Fix them! Hey do it in a natural way and let me age and die, take away the bad stuff! Don't let me live until 150 like I am a 25 year old.
Still in disbelief. It is like watching people in medieval times wanting to dunk the witch to see if she floats or drowns.
SENS Foundation - help stop age-related diseases
Quote: (05-19-2016 12:01 PM)Giovonny Wrote:
If I talk to 100 19 year old girls, at least one of them is getting fucked!
Quote:WestIndianArchie Wrote:
Am I reacting to her? No pussy, all problems
Or
Is she reacting to me? All pussy, no problems
Posts: 3,228
Threads: 0
Joined: Apr 2014
Reputation:
24
Science of Staying Young Forever - Google Is Now Involved
08-20-2016, 02:02 AM
Didn't they do this to a cow back in the day?
"A stripper last night brought up "Rich Dad Poor Dad" when I mentioned, "Think and Grow Rich""
Posts: 259
Threads: 0
Joined: Sep 2013
Reputation:
2
Science of Staying Young Forever - Google Is Now Involved
08-21-2016, 02:53 PM
Looking forward to more serious efforts being directed towards fighting aging. Hopefully we can stay ahead of the curve.
Posts: 424
Threads: 0
Joined: Jun 2015
Reputation:
5
Science of Staying Young Forever - Google Is Now Involved
08-21-2016, 03:03 PM
From The Economist :
Unless ageing is treated as an indication, anti-ageing drugs can’t get regulatory approval. And there’s little incentive to work on drugs you can’t sell.
If regulators were to change their stance, though, the interest would be immense. A condition that affects everyone is as big a potential market as can be imagined. And there are hints that the stance may indeed be changing. Two existing drugs approved for other purposes—metformin, widely used and well tolerated as a treatment for diabetes, and rapamycin, which reduces the risk of organ transplants being rejected—look to some researchers as though they might have broad anti-ageing effects not unlike those claimed for CR. In 2014 a study of 90,000 elderly patients with type 2 diabetes found that those receiving metformin had higher survival rates than matched non-diabetic controls. Other work has shown its use is associated with a decreased risk of cancer.
Scientists at the Institute for Ageing Research at the Albert Einstein College of Medicine, in New York, want to mount a trial of metformin in elderly subjects to see whether it delays various maladies (and also death). If that turns out to be the case, it will go a long way to showing that there is a generalised ageing process that can be modulated with drugs. Nir Barzilai, one of the researchers involved, says an important reason to do the trial is to have an indication against which next-generation ageing drugs can be assessed by regulators.
Posts: 1,315
Threads: 0
Joined: Feb 2016
Reputation:
3
Science of Staying Young Forever - Google Is Now Involved
08-21-2016, 03:29 PM
“As long as you are going to be thinking anyway, think big.” - Donald J. Trump
"I don't get all the women I want, I get all the women who want me." - David Lee Roth
Posts: 424
Threads: 0
Joined: Jun 2015
Reputation:
5
Science of Staying Young Forever - Google Is Now Involved
08-22-2016, 08:03 AM
More from The Economist:
One of these, resveratrol, caused a great deal of excitement among longevity researchers a few years ago because it kept mice on rich diets youthful. A lot of the initial interest has waned since it was discovered to be less helpful in mice that are not overweight, but it is still being investigated as an Alzheimer’s treatment.
David Sinclair of the Harvard Medical School, who was part of the initial enthusiasm, says
it has a number of targets within the cell. Among them are a set of proteins known as sirtuins which appear to be activated by resveratrol. Dr Sinclair created a company, Sirtris Pharmaceuticals, to investigate the potential of drugs aimed at these targets. GSK, a British pharma company which bought Sirtris in 2008, continues this work, though to date it has not yielded as much as was once hoped.
Sirtuins may act as metabolic sensors, and a number are found exclusively in the mitochondria, the structures in cells that look after respiration and which are central to the evolving concept of cellular ageing. Thomas von Zglinicki of Newcastle University says ageing cells are characterised by mitochondrial damage and have difficulty recycling damaged or broken cell machinery. They produce pro-inflammatory factors called cytokines which move neighbouring cells to senescence; chronic progressive inflammation of this sort drives various age-related diseases.
João Passos, also at Newcastle University, says cells from which mitochondria are removed start to look more like young cells and stop secreting cytokines. Other work has shown that killing off mitochondria can mimic some of the effects of drugs that activate mitochondrial renewal—such as rapamycin. Faster turnover of mitochondria seems to improve their functioning.
Data against death
Such discoveries in cell and molecular biology have perked up commercial interest in longevity. So too has data from the hundreds of thousands of human genome sequences. Dr Zhavoronkov’s Insilico Medicine, based in Baltimore, is using machine learning on vast piles of published genomic data to work out the differences between the tissues of young and old people and to look at how patterns of gene expression evolve as people age. It then looks in drug databases for molecules that might block the effects of the genes it thinks matter.