Unless its something really serious just play it off like you don't give a fuck. If the guy runs away after spilling at you stop compose yourself and give him a glare like you're going to rip his spine out, pause like that for a good 5 seconds, slowly turn to a girl and make a joke about her being wet (like 'gina wet not LOLURSOAKED wet). Like c'mon youre in the middle of making out and she gets covered in a drink PERFECT MOMENT TO SAY SOMETHING SEXUAL.
So in short my advice is to just laugh it off or use it to your advantage, be quick on your feet, be unyielding.
So in short my advice is to just laugh it off or use it to your advantage, be quick on your feet, be unyielding.