Financial District is a nice value play if you like luxury highrises. There are some good building with great amenities that cost a bit less than they might in other areas of the city. Also, nearly every train runa through, logistics are great. Also walkable to Soho, Tribeca, and Chinatown.
Otherwise, I would just go with West Village, Soho, Chelsea, Union Square or Flatiron.
Otherwise, I would just go with West Village, Soho, Chelsea, Union Square or Flatiron.