Quote: (05-19-2018 08:51 PM)Kreeba Wrote:
I have alopecia areata, I have been shaving it for a long time, it’s still show on my head, I have been using triamcinolone acetonide cream, that cream the doctor prescribed to me, it’s doesn’t work for me
You think any barber will do the jobs more then any razor blade. Any blade you guys recommends
I cant seem to shave everything off to a baldness, always miss some spots my clipper and razor doesnt graze off
First of all you need to eliminate grains, low fat dairy and legumes from your diet. AA is an autoimmune condition after all, and the proteins in these foods promote gut permeability and resulting autoimmunity, depending on your genetic variety. Also sugar (alcohol) and seed oils should be eliminated since they promote inflammation in the gut, and systemic as well. A full on Paleo diet is a must if you have any autoimmune disorder, including the various forms of skin and scalp disorders.
https://robbwolf.com/what-is-the-paleo-diet/
Secondly. What actually causes your hair to fall out is a process called fibrosis. As a result of the chronic inflammation mentioned, again resulting from the immune response and lymphocytes attacking your follicles. This involves among other things persistent inflammatory cytokine signaling. One of these cell communication signals is called transforming growth factor beta. (TGF-b) TGF recruits cells in your scalp called fibroblasts, who in response to inflammation differentiate and start to synthesize collagen fibers. This is a naturally occurring process that is constantly ongoing, and normally tightly regulated. The problem is the constant and unnatural inflammation, resulting from the dietary input, which is also unnatural. This causes excessive collagen production, that will eventually destroy the function of whatever tissue it effects. It`s the same process as with cirrhosis of the liver, dermal fibrosis or heart fibrosis etc. That`s why it`s so important to adjust your diet as soon as possible. To stop the destructive process.
There just might be a way of, partially at least, reversing fibrosis. The biology behind it is quite complicated, so I won`t go into it right now, but there is a product called TAM-818 spritzer, that via it`s effect on something called telomeres (The ends of your chromosomes, that get shorter each time the cells divide) could have a fibrosis reversing effect. Telomerase activation via gene therapy, which is a much more potent treatment, have been demonstrated to fully reverse fibrotic damage and restore tissue function.
https://www.news-medical.net/news/201801...-mice.aspx
You would basically have to study biology to understand just how this works, but I can recommend it at least.
TAM 818 has nothing to do with gene therapy, but it does promote some telomerase transcription. But it`s no good without the dietary interventions mentioned above. They will also stop the inflammation and thereby also the fibrotic process.
