Bumping this, because I know the bitter ennui of the long dark tea-time of the soul. And I don't want to dupe the thread and force Tuthmosis to wield his hammer of moderation.
When I was a young man, late teens to early 20's, I went through years of really struggling with depression. Bad, pitch-black depression, where I couldn't imagine a future for myself that didn't involve suicide or being sent to the loony bin.
This would alternate with periods where I felt invincible, unbeatable, wired with energy and able to do anything and talk anybody into anything.
But the bad days would always come back. It didn't matter if I was getting laid or not, or working out, or whatever. They always came back.
Like having a Radiohead concert in your brain
I never saw a doctor about it, which was foolish. I just gradually learned to cope with it, partly by learning to spot the pattern of downward-spiralling thoughts and try to consciously turn them around.
Music and humour are great tools for this. Listening to happy, upbeat tunes and deliberately trying to have a laugh - while avoiding sad songs and depressing news or films - helped.
Andre 3000 saved my life
I stopped watching or reading the news, because it made me sad and angry. This strategy worked quite well, but it wasn't completely effective. So I had a backup plan: self medication.
Booze helped me sleep. I was happy in the haze of a drunken hour, and embarked on a glorious career as a high functioning alcoholic. I still went to work every day, and did well. I wasn't hiding liquor in the toilet cistern or anything. But every night I was pounding beers, then whisky when the beer stopped working.
Of course, drunkeness is only a temporary solution. But hey - you can always get drunk again! So I did.
After about a decade of this, I went to the doctor one day for the results of a pee test for a minor unrelated complaint. He was pissed off.
My test results came back showing elevated enzyme levels related to the early stages of liver damage. The doctor told me to cut down on my drinking or I'd get serious liver damage and die. His advice was: "Son, you can drink yourself into an early grave if you want, but don't come crying to me when your organs start to fail. Sort your life out!"
Faced with this stark ultimatum from a respected medical professional I did what any champion alcoholic who no longer gets hangovers would do. I kept boozing for another two years.
But it was no longer fun. At the back of my mind, I kept worrying about pickling my liver with every sip of the finest Glenlivet.
So one day, I stopped. And it was awful.
Every hangover in my life came back to haunt me. I was fucked for two weeks of sweaty, achy, sleepless withdrawal. I was so weak and feverish I could barely lift a cat. My liver woke up angry after a decade of marinating in booze and it hurt like a bastard.
And the depression came back too.
No longer able to nuke it with alcohol, my happy thoughts tactic proved horribly ineffective. I had beaten the booze but not the underlying problem that made drinking so irresistible in the first place.
After about a year of trying to fix things myself - with St John's Wort and exercise and sunlight - I was fighting a losing battle. I was unhappy and becoming withdrawn. I couldn't sleep and stayed up most nights worrying about everything. My work started to suffer. My libido fell away faster than a man who has seen Lindy West naked. I wasn't coping.
So after two different doctors told me to try sertraline, I did.
It worked.
Most people don't need pills, but some of us do. In my case, a simple chemical tweak to increase the amount of naturally produced serotonin in my bloodstream makes the difference between being an unpleasant, miserable, unhappy dick and being a boisterous, brilliant, awesome dick.
TL;DR version: the drugs can work. If you're suffering, and nothing else is helping, consider seeing a doctor. And don't self medicate with booze unless you can afford a new liver.
Take it from me and Robert Downey Jr: crazy pills are better than being drunk off your arse all the time. And stay in school, kids!